Projects
The ACT Lab is dedicated to the development of innovative technologies that can enhance regeneration specifically in challenging contexts such as aged or metabolically compromised settings.
By bridging fundamental discoveries with translational applications, we aim to create effective regenerative therapies that improve the health and well-being of individuals facing these debilitating conditions.
07
REVERSE Proof Concept
Title: Modified extracellular vesicles for the delivery of microRNAs in diabetes
Principal Investigator: Hugo Fernandes
Funding agency/entity: CENTRO2030-FEDER-02360400
Period: February 2026 - July 2027
Budget: 119 662€
06
MATreSS
Title: Microfluidic-assisted tailored design of biodegradable composite fibres for wound dressings in burn care
Principal Investigator: Luis M. Bimbo
Co-PI: Hugo Fernandes
Funding agency/entity: COMPETE2030-FEDER-00670600: operation 15628
Period: November 2025 - November 2028
Budget: 206 366€
05
EVOLUTION
Title: Engineering the bioactivity and targeting potential of extracellular vesicles for the treatment of diabetes
Principal Investigator: Hugo Fernandes
Funding agency/entity: COMPETE2030-FEDER-00669700: operation 15621
Period: July 2025 - July 2028
Budget: 247 104€
04
Title: A test for early diagnosis of Congenital Hyperinsulinism (CHI)
Principal Investigator: Hugo Fernandes
Funding agency/entity: Horizon-WIDERA-2023-ACCESS-06, proposal number 101216499, LightCure-Hop
Period: May 2025 - December 2029
Budget: 547 895€
03
REVERSE
Title: Restoring beta cell function by engineering extracellular vesicles with microRNAs
Principal Investigator: Hugo Fernandes
Funding agency/entity: Fundação Santander and Universidade de Coimbra, Portugal
Period: January 2025 - December 2025
Budget: 20 000€
02
WOMEN IN SCIENCE, L'OREAL
Title: Women in Science, L'Oreal
Principal Investigator: Cláudia Deus
Funding agency/entity: L'Oreal
Period: June 2024
Budget: 15 000€
01
Title: miRNA-engineered EVs for the treatment of diabetic wounds
Principal Investigator: Hugo Fernandes
Funding agency/entity: Sociedade Portuguesa de Diabetologia
Period: March 2023 - March 2025
Budget: 5 000€
