Projects
The ACT Lab is dedicated to the development of innovative technologies that can enhance regeneration specifically in challenging contexts such as aged or metabolically compromised settings.
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By bridging fundamental discoveries with translational applications, we aim to create effective regenerative therapies that improve the health and well-being of individuals facing these debilitating conditions.
07
REVERSE Proof Concept
Title: Modified extracellular vesicles for the delivery of microRNAs in diabetes​
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Principal Investigator: ​​Hugo Fernandes
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Funding agency/entity: CENTRO2030-FEDER-02360400​
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Period: February 2026 - July 2027
Budget: 119 662€â€‹â€‹
06
MATreSS
Title: Microfluidic-assisted tailored design of biodegradable composite fibres for wound dressings in burn care
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Principal Investigator: ​​Luis M. Bimbo
Co-PI: Hugo Fernandes
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Funding agency/entity: COMPETE2030-FEDER-00670600: operation 15628​
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Period: November 2025 - November 2028
Budget: 206 366€â€‹â€‹
05
EVOLUTION
Title: Engineering the bioactivity and targeting potential of extracellular vesicles for the treatment of diabetes​​
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Principal Investigator: ​​Hugo Fernandes
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Funding agency/entity: COMPETE2030-FEDER-00669700: operation 15621
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Period: July 2025 - July 2028
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Budget: 247 104€
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04
Title: A test for early diagnosis of Congenital Hyperinsulinism (CHI)
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Principal Investigator: ​​Hugo Fernandes
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Funding agency/entity: Horizon-WIDERA-2023-ACCESS-06, proposal number 101216499, LightCure-Hop​
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Period: May 2025 - December 2029
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Budget: 547 895€
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03
REVERSE
Title: Restoring beta cell function by engineering extracellular vesicles with microRNAs
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Principal Investigator: ​​Hugo Fernandes
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Funding agency/entity: Fundação Santander and Universidade de Coimbra, Portugal​
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Period: January 2025 - December 2025
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Budget: 20 000€â€‹
02
WOMEN IN SCIENCE, L'OREAL
Title: Women in Science, L'Oreal
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Principal Investigator: ​​Cláudia Deus
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Funding agency/entity: L'Oreal​
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Period: June 2024
Budget: 15 000€
01
Title: miRNA-engineered EVs for the treatment of diabetic wounds
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Principal Investigator: ​​Hugo Fernandes
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Funding agency/entity: Sociedade Portuguesa de Diabetologia​
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Period: March 2023 - March 2025
Budget: 5 000€â€‹â€‹
