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Stay Connected with ACT Lab

At ACT Lab, we believe in sharing knowledge, fostering collaboration, and engaging with the scientific community and the public.

Below, we share a selection of articles that reflect the areas we are exploring and that inspire ongoing dialogue within our team and beyond.

Journal Club Papers

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

2025-06-25

Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence

2025-06-18

Metabolites released from apoptotic cells act as tissue messengers

2025-06-11

Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow-derived mesenchymal stem cells and slow age-related degeneration

2025-06-05

Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model

2025-05-13

In-situ mineralized homogeneous collagen-based scaffolds for potential guided bone regeneration

2025-04-10

Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies

2025-04-03

Stress-induced β cell early senescence confers protection against type 1 diabetes

2025-03-20

Milk exosomes-mediated miR-31-5p delivery accelerates diabetic wound healing through promoting angiogenesis

2025-03-13

Lithocholic acid phenocopies anti-ageing effects of calorie restriction

2025-03-06

Microbiota-Derived Extracellular Vesicles as a Postbiotic Strategy to Alleviate Diarrhea and Enhance Immunity in Rotavirus-Infected Neonatal Rats

2025-02-27

Exosomal miR-302b rejuvenates aging mice by reversing the proliferative arrest of senescent cells

2025-02-13

Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease

2025-01-29

Liraglutide reduces bone marrow adipogenesis by miR-150-5p/ GDF11 axis in diabetic rats

2025-01-16

Stem Cell Secretome and Its Effect on Cellular Mechanisms Relevant to Wound Healing

2024-12-04

Immune signatures of checkpoint inhibitor-induced autoimmunity—A focus on neurotoxicity

2024-11-25

PAHs increase the production of extracellular vesicles both in vitro in endothelial cells and in vivo in urines from rats

2024-11-15

Garcinol prevents oxidative stress-induced bone loss and dysfunction of BMSCs through NRF2-antioxidant signaling

2024-11-06

Small extracellular vesicles from senescent stem cells trigger adaptive mechanisms in young stem cells by increasing antioxidant enzyme expression

2024-10-24

Dysfunction of metabolic activity of bone marrow mesenchymal stem cells in aged mice

2024-10-17

Boosting the therapeutic potential of cell secretome against osteoarthritis: Comparison of cytokine-based priming strategies

2024-10-10

Mitochondrial DNA in extracellular vesicles declines with age

2024-05-17

Defining the activity of pro-reparative extracellular vesicles in wound healing based on miRNA payloads and cell type-specific lineage mapping

2024-03-21

Energy metabolism as therapeutic target for aged wound repair by engineered extracellular vesicle

2024-02-15

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